A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology
The CNRS bronze medal was awarded to Nadine Laguette in 2021
Biophysicists honored with Taiwan-France scientific prize
21st Franco-Taiwanese scientific grand prize was awarded jointly on November 27, 2019 in Paris to François Treussart and Chang Huan-cheng for their research, at the frontier of physics, chemistry and biology, on the use of fluorescent diamond nanocrystals in neuronal imaging. Awarded by the Taiwanese Ministry of Science and Technology and the Academy of Sciences in France, this prize rewards and encourages a Franco-Taiwanese scientific duo for their scientific contribution in a field of interest to both countries.
Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes.
Taffoni C, Steer A, Marines J, Chamma H, Vila IK and Laguette N. 2021.
Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing.
Front Immunol. 2021 Feb 23;12:637399. doi: 10.3389/fimmu.2021.637399. eCollection 2021. PMID: 33708225 Free PMC article. Review
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation.
Sci Adv. 2020 May 22;6(21):eaax3333. doi: 10.1126/sciadv.aax3333. eCollection 2020 May. PMID: 32494729
Animal Models for the Study of Nucleic Acid Immunity: Novel Tools and New Perspectives.
New look at RSV infection : tissue clearing and 3D imaging of the entire mouse lung at cellular resolution
Maxence Frétaud, Delphyne Descamps, Daphné Laubreton, Marie-Anne Rameix-Welti, Jean-François Eléouët, Thibaut Larcher, Marie Galloux, Christelle Langevin. doi: https://doi.org/10.1101/2020.12.23.424099
Control of polyunsaturated fatty acids desaturation by Sting regulates inflammatory responses
Isabelle K. Vila, Hanane Chamma, Alizée Steer, Clara Taffoni, Line S. Reinert, Evgenia Turtoi, Mathilde Saccas, Johanna Marines, Lei Jin, Xavier Bonnefont, Soren R. Paludan, Dimitrios Vlachakis, Andrei Turtoi, Nadine Laguette. bioRxiv 2020.12.22.423950; doi: https://doi.org/10.1101/2020.12.22.423950
Fluorescent ND for a traceable delivery of siRNA to mice