Professor Barbara Nawrot is a Principal Coordinator of Bioorganic Chemistry Department in the Centre of Molecular and Macromolecular Studies (Lodz, Poland), which is an institute of the Polish Academy of Sciences. She herself leads two units – Laboratory of Nucleic Acid Therapeutics and Anticancer Compounds Screening Laboratory. She obtained a PhD degree in organic chemistry at the Lodz University of Technology. Her post-doctoral training in Memorial Sloan Kettering Cancer Center (New York, USA), followed by intensive and fruitful work as a visiting researcher in the Department of Biochemistry at Bayreuth University (Germany) and therapeutic nucleic acids – related research at Gene Discovery Research Center, AIST (Tsukuba, Japan), shaped her scientific interest in the field of medicinal chemistry, especially chemistry and biology of nucleic acids. She is an expert in rare modifications of nucleic acids and their components, with strong involvement in research on interaction of modified models with biomolecules. The most frequent keywords characteristic for her publication over last 15 years have been: gene expression inhibitors (antisense oligonucleotides, DNA- and RNA-zymes, nanostructures of DNA with boron clusters), modified nucleosides in tRNA function, HIT proteins and their nucleotide inhibitors, anticancer compounds.
Barbara Nawrot : Centre of Molecular and Macromolecular Studies PAS